Medical requirements for South Africa

Malaria is absent from most parts of South Africa, and it is nowhere as prevalent as it is in much of equatorial Africa. Exceptions are the eastern lowveld of Mpumalanga and Limpopo, which is classified as a moderate-risk malarial area, and coastal KwaZulu-Natal north of Richard’s Bay, which is regarded to be low risk. Transmission is more-or-less confined to the rainy summer months. For this reason, travellers who intend to visit the Kruger National Park and/or adjacent private reserves from September to May are advised to take antimalarial drugs, and visitors to iSimangaliso Wetland Park and Hluhluwe-Imfolozi might also consider it. Several such drugs are available and it is best to seek advice from a doctor or travel clinic a few weeks before.

It is also advisable to take all reasonable precautions against being bitten by the nocturnal Anopheles mosquitoes that transmit the disease. Wear a long-sleeved shirt, trousers and socks in the evening, apply a DEET-based insect repellent to any exposed flesh, and sleep under a net, in an air-conditioned room, under a fan, or with a mosquito coil burning.

Travellers with young children or who prefer not to take medication could consider visiting one of several malaria-free safari destinations, for instance Madikwe, Pilanesberg or Addo, in preference to the Kruger National Park.


Popular South Africa Safaris

These popular itineraries can be customised to match your budget and travel dates

 | Magical Mauritius and South Africa Honeymoon Safari (11 days)

Magical Mauritius and South Africa Honeymoon Safari

Start your trip in South Africa and finish in Mauritius. Experience the stunning beaches and the Big Five in the Phinda Private Game Reserve. ...

 | Sabi Sand Game Reserve Safari (5 days)

Sabi Sand Game Reserve Safari (5 days)

You'll trek Africa's Big Five members in the Sabi Sand Game Reserve...

 | Two weeks in South Africa - a luxury rail safari

Two weeks in South Africa - a luxury rail safari

Experience the best that South Africa has to offer: it's white-sand beaches, lush green wine-lands and find the Big Five wildlife in the Kruger National Park. ...

 | South African Bush and Beach Journey (10 days)

South African Bush and Beach Journey (10 days)

Explore the magic of Cape Town followed by the Scenic Garden Route and finally the Big Five members at the Kruger National Park...

 | Luxury South Africa to Zimbabwe Safari (8 days)

Luxury South Africa to Zimbabwe safari (8 days)

Spot the Big Five in Thornybush Private Game Reserve and enjoy the majesty of Zimbabwe's roaring Victoria Falls ...

 | Botswana, Zimbabwe and South Africa Safari Adventure (19 days)

Botswana, Zimbabwe and South Africa Safari Adventure (19 days)

Africa safari adventure will take you to the tip of the African continent...

 | Big Five Safari in the Kruger National Park (3 days)

Big Five Safari in the Kruger National Park (3 days)

Encounter the Big Five safari and discover the elusive leopard...

 | Sabi Sands and Okavango Delta Big Five Tour (8 days)

Sabi Sands and Okavango Delta Big Five Tour (8 days)

Explore the famous reserve that offers exceptional game viewing and sight the elusive Sitatunga antelope in the Okavango ...

 | Cosmopolitan Cape Town and Kruger Tour (7 days)

Cosmopolitan Cape Town and Kruger Tour (7 days)

Discover the Big Cats in the Kruger National Park and enjoy the bustling harbour, world-class beaches and top-notch vineyards in Cape Town...

 | City and Safari in Southern Africa (14 days)

City and Safari in Southern Africa (14 days)

Majestic wildlife and the riches of Africa. ...

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