Medical requirements for South Africa

Malaria is absent from most parts of South Africa, and it is nowhere as prevalent as it is in much of equatorial Africa. Exceptions are the eastern lowveld of Mpumalanga and Limpopo, which is classified as a moderate-risk malarial area, and coastal KwaZulu-Natal north of Richard’s Bay, which is regarded to be low risk. Transmission is more-or-less confined to the rainy summer months. For this reason, travellers who intend to visit the Kruger National Park and/or adjacent private reserves from September to May are advised to take antimalarial drugs, and visitors to iSimangaliso Wetland Park and Hluhluwe-Imfolozi might also consider it. Several such drugs are available and it is best to seek advice from a doctor or travel clinic a few weeks before.

It is also advisable to take all reasonable precautions against being bitten by the nocturnal Anopheles mosquitoes that transmit the disease. Wear a long-sleeved shirt, trousers and socks in the evening, apply a DEET-based insect repellent to any exposed flesh, and sleep under a net, in an air-conditioned room, under a fan, or with a mosquito coil burning.

Travellers with young children or who prefer not to take medication could consider visiting one of several malaria-free safari destinations, for instance Madikwe, Pilanesberg or Addo, in preference to the Kruger National Park.


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Popular South Africa Safaris

These popular itineraries can be customised to match your budget and travel dates

 | Forray into the Wilderness of Sabi Sands and Madikwe  (7 days)

Forray into the Wilderness of Sabi Sands and Madikwe (7 days)

Our selection of South Africa's top safari lodges and game reserves are guaranteed to suit every taste and budget...

 | Best of Africa Safari (16 days)

Best of Africa Safari (16 days)

Experience the best of Africa, from the Okavango Delta – one of Africa's Seven Natural Wonders – to the endangered mountain gorillas and East Africa's Great Migration...

 | South African Bush and Beach Journey (10 days)

South African Bush and Beach Journey (10 days)

Explore the magic of Cape Town followed by the Scenic Garden Route and finally the Big Five members at the Kruger National Park...

 | Walking the Wild Coast of South Africa (8 days)

Walking the Wild Coast of South Africa (8 days)

Designed to offer a traditional hiking experience, but without the heavy bags, this "slackpacking" adventure is great for small groups or families. ...

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Experience Cape Town, the lush Cape Winelands and a safari in the Kruger National Park and you'll fall under South Africa's spell...

 | Blissful Fly-In Kruger Safari (4 days)

Blissful Fly-In Kruger Safari (4 days)

Experience luxury in the Kruger Park ...

 | Sabi Sand Game Reserve Safari (4 days)

Sabi Sand Game Reserve Safari (4 days)

You'll trek Africa's Big Five members in the Sabi Sand Game Reserve...

 | Cosmopolitan Cape Town and Kruger Tour (7 days)

Cosmopolitan Cape Town and Kruger Tour (7 days)

Discover the Big Cats in the Kruger National Park and enjoy the bustling harbour, world-class beaches and top-notch vineyards in Cape Town...

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Luxury South Africa to Zimbabwe safari (8 days)

Spot the Big Five in Thornybush Private Game Reserve and enjoy the majesty of Zimbabwe's roaring Victoria Falls ...

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