Medical requirements for South Africa

Malaria is absent from most parts of South Africa, and it is nowhere as prevalent as it is in much of equatorial Africa. Exceptions are the eastern lowveld of Mpumalanga and Limpopo, which is classified as a moderate-risk malarial area, and coastal KwaZulu-Natal north of Richard’s Bay, which is regarded to be low risk. Transmission is more-or-less confined to the rainy summer months. For this reason, travellers who intend to visit the Kruger National Park and/or adjacent private reserves from September to May are advised to take antimalarial drugs, and visitors to iSimangaliso Wetland Park and Hluhluwe-Imfolozi might also consider it. Several such drugs are available and it is best to seek advice from a doctor or travel clinic a few weeks before.

It is also advisable to take all reasonable precautions against being bitten by the nocturnal Anopheles mosquitoes that transmit the disease. Wear a long-sleeved shirt, trousers and socks in the evening, apply a DEET-based insect repellent to any exposed flesh, and sleep under a net, in an air-conditioned room, under a fan, or with a mosquito coil burning.

Travellers with young children or who prefer not to take medication could consider visiting one of several malaria-free safari destinations, for instance Madikwe, Pilanesberg or Addo, in preference to the Kruger National Park.


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Popular South Africa Safaris

These popular itineraries can be customised to match your budget and travel dates

 | City and Safari in Southern Africa (14 days)

City and Safari in Southern Africa (14 days)

Majestic wildlife and the riches of Africa. ...

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Blissful Fly-In Kruger Safari (4 days)

Experience luxury in the Kruger Park ...

 | Best of Africa Safari (16 days)

Best of Africa Safari (16 days)

Experience the best of Africa, from the Okavango Delta – one of Africa's Seven Natural Wonders – to the endangered mountain gorillas and East Africa's Great Migration...

 | Two weeks in South Africa - a luxury rail safari

Two weeks in South Africa - a luxury rail safari

Experience the best that South Africa has to offer: it's white-sand beaches, lush green wine-lands and find the Big Five wildlife in the Kruger National Park. ...

 | The Ultimate Big Five South African Safari (7 days)

The Ultimate Big Five South African Safari (7 days)

Get the best possible chance to see the Big Five wildlife in the iconic Kruger National Park and Manyeleti Game Reserve ...

 | South African Holiday Adventure (10 days)

South African Holiday Adventure (10 days)

Explore the southern-most city on the African continent, before jetting off to spot the Big Five...

 | Kruger to the Mozambican Coast (7 days)

Kruger to the Mozambican Coast (7 days)

Combining the bush and the wildlife found in the famous Sabi Sand in the Kruger National Park with a tropical stay in one of the sublime lodges of Mozambique's Ponta Mamoli...

 | Affordable Cape Town, Kruger National Park and Victoria Falls Luxury Safari (10 days)

Affordable Cape Town, Kruger National Park and Victoria Falls Luxury Safari (10 days)

Visit the most popular destinations in Southern Africa on this luxury tour for the budget-conscious...

 | Kruger, Cape Town and Mauritius Bush & Beach Safari (15 days)

Kruger, Cape Town and Mauritius Bush & Beach Safari (15 days)

Spend your days discovering the fine beaches of Cape Town, enjoying the remarkably untamed wilderness of the Kruger National Park and swimming the pristine beaches of Mauritius....

 | Luxurious Cape Town and Victoria Falls Tour (8 days)

Luxurious Cape Town and Victoria Falls Tour (8 days)

Two countries in 8 days may seem like a lot but with this well thought out itinerary you will see some of the regions most iconic destinations without feeling like you are rushing through it…

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