An aardvark in the malaria-free Kichaka Game Reserve in the Eastern Cape
Although malaria is a major travel concern in much of Africa, it has a very limited presence in South Africa. Indeed, more than 95% of South Africa, and most of its major attractions, are entirely free of malaria. There are only two exceptions. The eastern lowveld of Mpumalanga and Limpopo, which includes the Kruger National Park and associated private reserves, is classified as moderate risk.
Rhinos in the Hluhluwe-Imfolozi Game Reserve. This is another malaria-free safari destination
Then there is coastal KwaZulu-Natal, north of Richards Bay, which is regarded to be low risk and includes iSimangaliso Wetland Park and Hluhluwe-Imfolozi Game Reserve.
Transmission in these areas is more-or-less confined to the rainy summer months. Most other safari destinations in South Africa are malaria-free, notably Madikwe and Pilanesberg Game Reserves, and Addo Elephant National Park. There is also no malaria in other popular areas such as Cape Town, the Cape Winelands, the Garden Route, Durban and the KwaZulu-Natal south coast, the uKhahlamba-Drakensberg and Johannesburg.